Valerian extract
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Basic information
Product Name: Valerian extract
Appearance: Brown to yellow powder or granular
Standard Packing: 25kg/drum
Solubility: Dissolve in water and ethanol.
Source & Botanical Characteristics:
Scientific Name:Valeriana officinalis L.
Aliases: Garden valerian, All-heal (wild varieties in Northeast China)
Medicinal Parts: Underground rhizomes (optimal harvest: 2-3 year-old roots in autumn)
Distribution: Temperate regions of Europe/Asia; native to Heilongjiang/Jilin, China
Key Identification Features:
Pinnate opposite leaves, corymbose cyme inflorescence
Distinctive earthy odor (fresh roots) turning sandalwood-like when dried
Standard: CP2020,JP,Customer Made
Core Active Components
1 .Characteristic Compounds
Category |
Representative Compounds |
Content Range |
Biological Activity |
Iridoids |
Valepotriates |
0.5-2.0% |
Sedative (enhances GABA receptor activity) |
Acvaltrate |
0.3-1.2% |
Anxiolytic (modulates 5-HT1A receptors) |
|
Essential Oils |
Valerenic acid |
0.2-0.8% |
Improves sleep quality (extends NREM sleep) |
Valerenal |
0.1-0.5% |
Antispasmodic (smooth muscle relaxation) |
|
Alkaloids |
Valerianine |
0.05-0.3% |
Antihypertensive (calcium channel blockade) |
2.Synergistic Effects
Valepotriates + Limonene: 3× enhanced sedative effect
Valerenic acid + GABA: 40% reduction in sleep latency
High Purity
100% Natural
Compliant with standards
Stable supplying
Quality ensured
Versatile Applications
Sedative-Hypnotic Mechanism
Targets:
Increases GABA_A receptor chloride channel opening frequency
Inhibits glutamatergic neuron hyperexcitability
Clinical Data:450 mg/day × 4 weeks improved sleep efficiency by 35% (PSQI scores)
Anxiolytic Effects
Animal Study: Elevated plus maze showed 2× longer open arm duration
Cardiovascular Protection
Reduces SBP by 10-15 mmHg (SHR model)
65% inhibition of ADP-induced platelet aggregation
Application Fields Green max
1. Pharmaceutical Sector:
Sedative-Hypnotics: Combined with hops extract (improves sleep architecture)
Anxiolytics: Paired with passionflower extract (reduces benzodiazepine dependence)
2.Functional Foods:
Calming Teas: Valerian + chamomile blend (mild anxiety relief)
Sports Recovery: Lowers cortisol levels (post-competition use)
3.Cosmetics:
Soothing Serums: 0.2% valerenic acid (TRPV1 inhibition for sting relief)
Hair Growth: Promotes follicular proliferation (outperforms minoxidil)
Structural Optimization
Valepotriate derivatives (enhanced BBB penetration)
Delivery Systems
Sublingual fast-dissolving films (15-minute onset)
New Indications
Adjunctive epilepsy treatment: Preclinical shows 40% seizure reduction
Usage Guidelines
Recommended Dosage
Purpose |
Daily Dose |
Optimal Timing |
Synergistic Combinations |
Insomnia |
400-600 mg |
30 mins before bed |
Melatonin 1 mg |
Generalized Anxiety |
300-450 mg |
Morning & evening |
L-Theanine 200 mg |
PMS |
250 mg |
10 days pre-menses |
Evening primrose oil 1 g |
Precautions
Limit continuous use to 3 months (prevents receptor downregulation)
Alcohol potentiates sedative effects
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