Pueraria lobata Extract
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Basic information
Product Name: Pueraria lobata Extract
Appearance: Brown to white powder or granular
Standard Packing: 25kg/drum
Solubility: Dissolve in water and ethanol.
Stability: Puerarin is prone to oxidation when exposed to light (should be stored away from light)
High temperature (>70 ℃) may degrade active ingredients
The weakly acidic environment (pH 5-6) is the most stable
Quality Standard: CP2020,JP,Customer Made
Main active ingredients
The core active ingredients of Pueraria lobata extract include isoflavones, saponins, and polysaccharides, and its unique efficacy is closely related to the synergistic effect of these ingredients.
|
Ingredient category |
Representative components |
Molecular formula |
CAS |
Proportion of Content |
Main function |
|
Isoflavones |
Puerarin |
C₂₁H₂₀O₉ |
3681-99-0 |
2%~8% |
Cardiovascular protection and antioxidant properties |
|
Daidzin |
C₂₁H₂₀O₉ |
552-66-9 |
0.5%~2% |
estrogen-like effect |
|
|
Genistein |
C₁₅H₁₀O₅ |
446-72-0 |
0.1%~0.5% |
Antitumor and metabolic regulation |
|
|
Saponins |
Kudzusaponin A |
C₅₈H₉₄O₂₇ |
118525-40-9 |
0.3%~1.2% |
Anti inflammatory and liver protective |
|
Polysaccharides |
Pueraria polysaccharide |
(C₆H₁₀O₅)ₙ |
/ |
10%~15% |
immunoregulation |
High Purity
100% Natural
Compliant with standards
Stable supplying
Quality ensured
Versatile Applications
Application Fields Green max
1. Pharmaceutical preparations
● Puerarin Injection: Treatment of Coronary Heart Disease and Angina Pectoris (included in the Chinese Pharmacopoeia)
● Hangover medicine: Compound with curcumin and glutathione
2. Functional Foods
● Hangover drink: Add 0.1-0.3% kudzu root extract
● Menopausal health products: combined with black cohosh extract
3. Cosmetics
● Anti aging essence: puerarin antioxidant (ORAC value 15000 μ mol TE/g)
● Whitening products: Inhibit tyrosinase activity
Future R&D Directions
1. Structural Optimization:
● Puerarin prodrug (acetylation): ↑Oral bioavailability from 8% to 35%
2. Synthetic Biology:
● Yeast fermentation: Lab-scale puerarin production reaches 0.8g/L
3. New Clinical Applications:
● Diabetic retinopathy: Phase II trials show 38% reduction in microvascular leakage
Safety Profile
1. Toxicology:
● Acute toxicity: LD50 >5g/kg (practically non-toxic)
● Genotoxicity: Negative in Ames/micronucleus tests
2. Drug Interactions:
● Potentiation: Antihypertensives (requires BP monitoring)
● Contraindications: Estrogen medications (possible synergy)
Usage Guidelines
1. Precision Dosing
Application |
Daily Dose |
Duration |
Optimal Combinations |
Cardiovascular care |
250-300 mg |
3+ months |
Coenzyme Q10 |
Alcohol detox |
500 mg pre-drinking |
Acute use |
Silymarin |
Menopausal symptoms |
200 mg bid |
≥12 weeks |
Vitamin E |
2. Precautions:
● Dose adjustment for hypotensive patients
● Caution during pregnancy (estrogenic effects)
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