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Polygonum cuspidatum extract
Plant Extract

Polygonum cuspidatum extract

Polygonum cuspidatum, also known as Japanese tiger cane or tiger cane root, is a plant in the Polygonaceae family. Its rhizome is rich in various active ingredients and is widely used in traditional Chinese medicine (TCM) and modern medicine. The extract of Polygonum cuspidatum mainly contains components such as resveratrol, Emodin, Polydatin, etc. It has various biological activities such as antioxidant, anti-inflammatory, antibacterial, hepatoprotective, and anti-tumor.

Product Name: Polygonum cuspidatum extract

Appearance: White or off -white powder or granular

Standard Packing: 25kg/drum

Solubility: Dissolve in water and ethanol

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    Polygonum cuspidatum extract

    Basic information

    Product Name: Polygonum cuspidatum extract

    Appearance: White or off -white powder or granular

    Standard Packing: 25kg/drum

    Solubility: Dissolve in water and ethanol.

    Stability: Resveratrol is easily oxidized by light

    High temperature (>70 ℃) accelerates component degradation

    Neutral to weakly acidic environment (pH 5-7) is the most stable

    Quality Standard: CP2020,JP,Customer Made

    Core Active Components

    The core active ingredients of Polygonum cuspidatum extract include stilbenes, anthraquinones, and flavonoids.

    Ingredient category

    Representative components

    Molecular formula

    CAS

    Proportion of Content

    Main function

    Qi class

    Resveratrol

    C₁₄H₁₂O₃

    501-36-0

    1-5%

    Antioxidant and anti-aging properties

    Polydatin

    C₂₀H₂₂O₈

    27208-80-6

    3-10%

    cardiovascular protection

    Anthraquinones

    Emodin

    C₁₅H₁₀O₅

    518-82-1

    0.5-3%

    Antibacterial, diarrhea

    Chrysophanol

    C₁₅H₁₀O₄

    481-74-3

    0.3-1.5%

    anti-tumor

    Flavonoids

    Quercetin

    C₁₅H₁₀O₇

    117-39-5

    0.5-2%

    Anti inflammatory and anti allergic

    Product Advantages

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    High Purity

    Advanced extraction ensures: Polygonum cuspidatum extract content for maximum efficacy.
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    100% Natural 

    No artificial additives, non-GMO, safe for long-term use.
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    Compliant with standards

    The pesticide residue, Heavy metals and PAHs etc of products meet up with EU standard.
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    Stable supplying

    We can treat raw materials with capacity of 5000tons per year.
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    Quality ensured

    We test each batch with assay, loss on drying, total ash, heavy metals, bacterium and provide report from third party.
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     Versatile Applications

    Suitable for supplements, skincare, and functional foods.

    Pharmacological effects and efficacy

    Anti-Inflammatory Mechanism

    Free radical scavenging:
    ORAC value ≥ 20000 μ mol TE/g
    Activate SIRT1 longevity gene

    Skin protection:
    Inhibition of MMP-1 collagenase activity
    Reduce UV damage

    Cardiovascular Protection

    Improving microcirculation:
    Resveratrol glycoside promotes NO production
    Reduce blood viscosity

    Regulating blood lipids:
    Reduce LDL (15-20%)
    Elevated HDL (10-15%)

    Antibacterial and antiviral effects

    Antibacterial spectrum:
    Staphylococcus aureus (MIC 50 μ g/mL)
    Candida albicans (MIC 100 μ g/mL)

    Antiviral:
    Inhibit influenza virus replication
    Block HSV-1 adsorption

    Application Fields Green max

    1. Medical and Health Care

    Anti aging products:
    Resveratrol capsules (100-300mg/day)
    Compound antioxidant preparation

    Cardiovascular health:
    Improving Microcirculation Tablets
    Lipid lowering formula

    2. Cosmetics

    Anti aging skincare products:
    Anti wrinkle essence (0.5-1% resveratrol)
    Sunscreen Products

    Acne products:
    Utilizing the antibacterial effect of emodin
    Oil control and anti-inflammatory formula

    3. Functional Foods

    Health drinks:
    Antioxidant beverage
    Alcohol relieving and liver protecting products

    Food additives:
    natural preservative
    Functional pigment

    Polygonum cuspidatum

    Future R&D Directions​

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    Structural Optimization

    Resveratrol prodrug (propylene glycol ester): ↑Oral bioavailability from <1% to 25

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    Synthetic Biology

    E. coli engineering: Lab-scale polydatin production reaches 1.5g/L

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    New Clinical Applications

    NAFLD: Phase II trials show 27% ↓hepatic fat content

    Usage Guidelines​

    1. Precision Dosing​

    ​Application​

    ​Daily Dose​

    ​Duration​

    ​Optimal Combinations

    Antioxidant

    100-200 mg

    3+ months

    Vitamin C + E

    Cardiovascular

    300 mg

    Long-term

    CoQ10

    Skincare

    Topical 1-2%

    Daily

    Hyaluronic acid

    Precautions

    Caution during pregnancy (potential uterine stimulation by emodin)

    Avoid grapefruit juice (CYP3A4 inhibition synergy)

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