Macleaya cordata extract
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Basic Information
Product Name: Berberine hydrochloride
Appearance: Yellow crystalline powder
Molecular formula: C20H18ClNO4
Molecular weight: 372.822
CAS No.: [633-65-8]
Standard Packing: 25kg/drum
Solubility: Easily soluble in boiling water, slightly soluble in cold water, and almost insoluble in cold ethanol, chloroform, and ether
Quality Standard: CP2020, JP, Customer Made
Main active ingredients
The core active ingredients of Boluohui extract are benzophenanthridine alkaloids, among which Sanguinarine and Chelerythrine have the highest content, accounting for 50%~80% of the total alkaloids.
Alkaloid name |
Molecular formula |
CAS |
Proportion of Content |
Main function |
Sanguinarine |
C₂₀H₁₄NO₄⁺ |
2447-54-3 |
30%~50% |
Antibacterial and antiparasitic |
Chelerythrine |
C₂₁H₁₈NO₄⁺ |
34316-15-9 |
20%~40% |
Anti inflammatory and anti-tumor |
Protopine |
C₂₀H₁₉NO₅ |
130-86-9 |
5%~10% |
Analgesia and anti-inflammatory |
Allocryptopine |
C₂₁H₂₃NO₅ |
485-91-6 |
3%~8% |
antiarrhythmic |
Pharmacological effects and efficacy
1. Broad spectrum antibacterial
Mechanism of action: destroys bacterial cell membrane, interferes with DNA replication
Sensitive pathogens:
Gram positive bacteria (Staphylococcus aureus, Streptococcus)
Fungi (Candida albicans)
Parasites (coccidiosis, roundworms)
Porcine dysentery spirochetes (prevention and treatment of swine dysentery)
2. Anti inflammatory and immune regulation
Inhibiting the NF - κ B pathway and reducing the release of inflammatory factors such as TNF - α and IL-6
3. Growth promoting effect (for animal use)
Improving intestinal health of livestock and poultry, increasing feed conversion rate (replacing antibiotics)
4. Antitumor Activity (Research Stage)
Inducing apoptosis of tumor cells (by activating the Caspase-3 pathway with sanguinarine)
Application Fields Green max
1. Veterinary drugs and feed additives
Pig/chicken feed (0.5-2g/kg) for preventing and treating diarrhea and coccidiosis
Aquaculture (inhibition of Vibrio, prevention and treatment of white stool syndrome in shrimp)
2. Pesticides
Natural plant-based insecticides (for controlling aphids and spider mites)
3.Pharmaceutical Research and Development
Oral antibacterial preparations (toothpaste, mouthwash)
Lead compounds of anti-tumor drugs
4. Cosmetics
Acne removing ingredients (inhibiting Propionibacterium acnes)
Application Solutions
Recommended Dosage
● Feed additive: 50-150g/ton for livestock, 100-200g/ton for aquaculture
● Pesticide use: 500-1000x dilution for spray
Precautions
※ Pharmaceutical applications require professional guidance
※ Avoid combination with strong oxidizers
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