Licorice extract
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Basic information
Product Name: Licorice extract
Appearance: Brown to yellow powder or granular
Standard Packing: 25kg/drum
Solubility: Dissolve in water and ethanol.
Source & Botanical Characteristics:
● Scientific Name: Glycyrrhiza uralensis (Chinese licorice) / G. glabra (European licorice)
● Aliases: Sweet root (50× sweeter than sucrose), Gan Cao
● Medicinal Parts: Main root & stolons (highest potency in 3-4 year-old plants)
● Distribution: Northwest/North China, Central Asia, Mediterranean
● Key Identification Features:
Pinnate compound leaves with papilionaceous purple-red flowers
Red-brown bark with yellow cross-section, distinct sweet flavor
Standard: CP2020,JP,Customer Made
Core Active Components
1. Characteristic Compounds
|
Category |
Representative Compounds |
Content Range |
Biological Activity |
|
Triterpenoid Saponins |
Glycyrrhizic acid |
4-12% |
Antiviral (inhibits SARS-CoV-2 replication) |
|
Glycyrrhetinic acid |
0.5-2% |
Anti-inflammatory (COX-2 inhibition) |
|
|
Flavonoids |
Liquiritin |
0.3-1.5% |
Antioxidant (free radical scavenging) |
|
Isoliquiritigenin |
0.1-0.8% |
Antitumor (apoptosis induction) |
|
|
Polysaccharides |
Glycyrrhiza Polysaccharide (GPS) |
5-10% |
Immunomodulation (macrophage activation) |
2. Synergistic Effects:
● Glycyrrhizic acid + Vitamin C: 3× enhanced antiviral activity
● Isoliquiritigenin + 5-FU: 40% improved anticancer efficacy
High Purity
100% Natural
Compliant with standards
Stable supplying
Quality ensured
Versatile Applications
Application Fields Green max
1. Pharmaceutical Sector:
● Antiviral Drugs: Ammonium glycyrrhizinate injections (chronic hepatitis B treatment)
● Antitussives: Synergistic effect with bitter almond extract
2. Functional Foods:
● Liver Protection Tablets: Combined with schisandrin (2× ALT reduction)
● Sugar Substitute: Glycyrrhizin (50× sweeter than sucrose)
3. Cosmetics:
● Anti-Redness Serums: 0.5% dipotassium glycyrrhizinate (75% redness reduction)
● Whitening Creams: Superior tyrosinase inhibition to arbutin
Future R&D Directions
1.Structural Modification:
● 18β-glycyrrhetinic acid derivatives (reduced pseudoaldosterone effects)
2. Delivery Systems:
● Exosome-based drug carriers (6× improved liver targeting)
3. New Indications:
● Atopic dermatitis: Phase II showed 40% SCORAD index reduction
Safety Profile
1. Toxicology:
● Acute Toxicity: LD50＞5 g/kg (practically non-toxic)
2. Contraindications:
● Caution in hypertension (sodium retention risk)
● Potassium supplementation required with diuretics
Usage Guidelines
1. Precision Dosing
|
Purpose |
Daily Dose |
Duration |
Synergistic Combinations |
|
Chronic Hepatitis |
150-300 mg |
3-6 months |
Silymarin 200 mg |
|
Respiratory Inflammation |
200 mg |
7-day acute phase |
Scutellaria extract 100 mg |
|
Skin Anti-Irritation |
50 mg |
≥8 weeks |
1% Ceramide |
2. Precautions:
● Maximum 8-week continuous use
● Take with meals (enhanced absorption)
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