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Honeysuckle extract
Plant Extract

Honeysuckle extract

Honeysuckle extract is a natural bioactive component derived from the flower buds or newly bloomed flowers of ​Lonicera japonica​ (Caprifoliaceae family), primarily containing ​chlorogenic acid​ and ​luteoloside. Recognized as the "top heat-clearing and detoxifying herb" in Chinese pharmacopoeia, its antiviral, antibacterial, and immunomodulatory properties are validated by both traditional and modern medicine, making it a highly effective natural ingredient for influenza prevention and skincare.

Product Name: Honeysuckle extract 

Appearance: Brown yellow powder or granular

Standard Packing: 25kg/drum

Solubility: Dissolve in water and ethanol

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    Honeysuckle extract

    Basic information

    Product Name: Honeysuckle extract

    Appearance: Brown yellow powder or granular

    Standard Packing: 25kg/drum

    Solubility: Dissolve in water and ethanol.

    Source & Botanical Characteristics:
    Scientific Name:Lonicera japonica Thunb.
    Aliases: Shuanghua, Erbao flower (named for its color change from white to yellow)
    Medicinal Parts: Flower buds (best harvested when green-white and unopened)
    Distribution:Nationwide in China; Henan/Shandong are premium production areas

    Key Features:
    Bilabiate corolla, white when first bloomed then turning golden
    Climbing vine with hollow stems

    Standard: CP2020,JP,Customer Made

    Main active ingredients

    1. Characteristic Compounds​

    ​Category​

    ​Representative Compounds​

    ​Content Range​

    ​Biological Activity​

    ​Phenolic Acids​

    Chlorogenic acid

    3.0-7.5%

    Antiviral (inhibits viral replicase)

    Caffeic acid

    0.5-1.8%

    Anti-inflammatory (COX-2/PGE2 inhibition)

    ​Flavonoids​

    Luteoloside

    1.2-3.5%

    Antioxidant (ROS/free radical scavenging)

     

    Lonicerin

    0.3-1.2%

    Anti-allergic (histamine release inhibition)

    ​Iridoids​

    Loganin

    0.1-0.6%

    Hepatoprotective (CYP2E1 inhibition)

    2. Synergistic Effects:

    Chlorogenic acid + Zinc ions: 4× enhanced anti-influenza activity

    Luteoloside + Vitamin C: 70% increased free radical scavenging rate

    Product Advantages

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    High Purity

    Advanced extraction ensures Honeysuckle extract  content for maximum efficacy.
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    100% Natural 

    No artificial additives, non-GMO, safe for long-term use.
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    Compliant with standards

    The pesticide residue, Heavy metals and PAHs etc of products meet up with EU standard.
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    Stable supplying

    We can treat raw materials with capacity of 5000tons per year.
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    Quality ensured

    We test each batch with assay, loss on drying, total ash, heavy metals, bacterium and provide report from third party.
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     Versatile Applications

    Suitable for supplements, skincare, and functional foods.

    Pharmacological effects and efficacy

    Antiviral Effects​

    Mechanisms:
    Blocks influenza virus hemagglutinin binding
    Inhibits SARS-CoV-2 3CL protease (IC50=8.2μM)

    Clinical Data:
    600 mg/day × 5 days reduced flu duration by 2.3 days

    Anti-Inflammatory Immunomodulation

    Animal Study: 55% lower inflammation scores in LPS-induced pneumonia

    Anti-Inflammatory Immunomodulation

    Hepatoprotection

    Reduces ALT/AST in CCl4 liver injury models (outperforms silymarin)

    Enhances glutathione-S-transferase activity (↑40% detox capacity)

    Application Fields Green max

    1. Pharmaceutical Sector:
    Antiviral Formulations: Core component of Lianhua Qingwen capsules
    Anti-Inflammatory: Alternative to antibiotics for pharyngitis/tonsillitis

    2. Functional Foods:
    Immune Boosters: Combined with lentinan (↑25% IgG levels)
    Hangover Protection: With puerarin (↑30% alcohol metabolism)

    3. Cosmetics:
    Anti-Acne Serums: 1% extract (MIC=50μg/mL against C. acnes)
    Soothing Masks: TRPV1 desensitization (80% redness reduction)

    Honeysuckle

    Future R&D Directions​

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    Structural Modification

    Zinc-chlorogenate complexes (prolongs oropharyngeal retention)

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    Delivery Systems

    Nhalable liposomes (targets respiratory viral infections)

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    New Indications

    Atopic dermatitis: Preclinical shows ↓50% IL-4/IL-13 expression

    Usage Guidelines​

    Recommended Dosage​

    ​Purpose​

    Daily Dose

    Duration

    Synergistic Combinations

    Cold Prevention

    300-500 mg

    Seasonal

    Vitamin C 500 mg

    Viral Hepatitis

    600 mg

    3-6 months

    Silymarin 200 mg

    Skin Inflammation

    2% topical

    Twice daily

    Ceramide 1%

    Precautions

    Store airtight in dark (chlorogenic acid is light-sensitive)

    Brewing temperature ≤80°C (prevents thermolabile degradation)

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