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Ginkgo biloba extract
Plant Extract

Ginkgo biloba extract

Ginkgo biloba extract is an active compound derived from the dried leaves of the maidenhair tree (Ginkgo biloba L.), renowned for its ​microcirculation improvement, antioxidant, and neuroprotective​ properties. As one of the world's best-selling botanical medicines, it is widely used in cardiovascular disease prevention, cognitive enhancement, and anti-aging applications.

Product Name: Ginkgo biloba extract

Appearance: Brown to yellow powder or granular

Standard Packing: 25kg/drum

Solubility: Dissolve in water and ethanol.

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    Ginkgo biloba extract

    Basic information

    Product Name: Ginkgo biloba extract

    Appearance: Brown to yellow powder or granular

    Standard Packing: 25kg/drum

    Solubility: Dissolve in water and ethanol.

    Ginkgo biloba extract:

    Scientific Name: Ginkgo biloba L. (the only surviving species in the Ginkgoaceae family)

    Medicinal Part: Mature leaves harvested in autumn

    Primary Production Regions: China (accounts for 90% of global production), France, Germany

    Extraction Process: Acetone-water extraction → Ginkgolic acid removal → Standardized concentration

    Standard: CP2020,JP,Customer Made

    Roots​ – Richer in active compounds but require longer growth cyclesQuality Standard: CP2020,JP,Customer Made

    Core Active Components

    1. Characteristic Compounds​

    ​Class​

    ​Representative Compounds​

    Content Range​

    ​Bioactivity​

    Flavonoid Glycosides​

    Quercetin-3-O-glucoside

    5-12%

    Antioxidant (O₂⁻ scavenging)

    Kaempferol-3-O-rhamnoside

    3-8%

    Anti-inflammatory (NF-κB inhibition)

    ​Terpene Lactones​

    Ginkgolide A

    0.5-1.5%

    PAF receptor antagonism (antithrombotic)

    Ginkgolide B

    0.3-1.2%

    Neuroprotection (↓excitotoxicity)

    Bilobalide

    0.2-0.8%

    Mitochondrial protection (anti-apoptotic)

    ​Organic Acids​

    Ginkgolic acid

    ≤5 ppm

    Allergen (strictly controlled)

    2.Synergistic Effects:

    Flavonoids + terpene lactones: 3× better cerebral blood flow improvement

    Bilobalide + zinc: 2.5× enhanced neuroprotection

    Product Advantages

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    High Purity

    Advanced extraction ensures :Ginkgo biloba extract content for maximum efficacy.
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    100% Natural 

    No artificial additives, non-GMO, safe for long-term use.
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    Compliant with standards

    The pesticide residue, Heavy metals and PAHs etc of products meet up with EU standard.
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    Stable supplying

    We can treat raw materials with capacity of 5000tons per year.
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    Quality ensured

    We test each batch with assay, loss on drying, total ash, heavy metals, bacterium and provide report from third party.
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     Versatile Applications

    Suitable for supplements, skincare, and functional foods.

    Multitarget Pharmacological Activities

    Cardiovascular Protection

    Microcirculation improvement:
    Inhibits PAF-induced platelet aggregation (IC50=0.8 μM)
    Clinical data: 120mg/day ×8 weeks → 35% ↑cerebral blood flow

    Anti-atherosclerotic:
    40% ↓endothelial ICAM-1 expression
    30% ↓MMP-9 activity (plaque stabilization)

    Neuroprotective Mechanisms

    Multitarget Pharmacological Activities

    Clinical Trials: Alzheimer's patients show 2.5-point MMSE improvement (24 weeks)

     Sensory Function Enhancement

    25% ↑retinal blood flow (diabetic patients)

    15dB hearing threshold improvement (age-related hearing loss)

    Application Fields Green max

    1. Pharmaceuticals:
    ​Cerebrovascular disease: Ginkgolide injections (acute stroke management)
    ​Dementia treatment: Sustained-release tablets (30% slower AD progression)

    2. Functional Foods:
    ​Eye health: Combined with lutein (retinal microcirculation improvement)
    ​Anti-fatigue: With ginsenosides (12% ↑VO₂max)

    3.Cosmetics:
    ​Anti-redness serums: 1% ginkgo flavonoids + asiaticoside
    ​Anti-hair loss shampoos: 2% extract (35% ↑follicle survival rate)

    Ginkgo biloba

    Future R&D Directions

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    Structural Optimization

    PEGylated ginkgolide B: 5× better blood-brain barrier penetration
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    Synthetic Biology

    Tobacco cell culture production (lab yield: 1.2g/L ginkgolides)
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    New Clinical Applications

    Glaucoma: Phase II shows 22% ↓intraocular pressure

    Usage Guidelines​

    Precision Dosing

    ​Application​

    Daily Dose​

    Duration​

    Optimal Combinations

    Cerebral circulation

    120-160 mg

    ≥3 months

    Coenzyme Q10

    Dementia prevention

    240 mg

    Long-term

    Phosphatidylserine

    Retinal protection

    80 mg

    Continuous

    Lutein

    Precautions

    Discontinue 2 weeks pre-surgery (bleeding risk)

    Avoid high-dose aspirin combinations

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