Eucommia ulmoides extract
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Basic information
Product Name: Eucommia ulmoides extract
Appearance: Brown to yellow powder or granular
Standard Packing: 25kg/drum
Solubility: Dissolve in water and ethanol.
Stability: Flavonoids are prone to photolysis (need to be stored away from light)
High temperature (>60 ℃) may degrade active ingredients
Neutral to weakly acidic environment (pH 5-7) is the most stable
Quality Standard: CP2020,JP,Customer Made
Main active ingredients
The core active ingredients of Eucommia ulmoides extract include Organic acids， lignans, iridoids, flavonoids, polysaccharides, and Eucommia ulmoides gum. Among them, Pinorsinol Diglucoside (PDG) is the main quality control indicator.
|
Ingredient category |
Representative components |
Molecular formula |
CAS |
Proportion of Content |
Main function |
|
Organic acids |
Chlorogenic acid |
C₁₆H₁₈O₉ |
327-97-9 |
0.1%~1% |
Antioxidant and lipid-lowering properties |
|
Lignans |
Turpentine alcohol diglucoside |
C32H42O16 |
63902-38-5 |
0.5%~3% |
Lowering blood pressure and antioxidation |
|
Lilac resin alcohol diglucoside |
C32H42O16 |
69286-96-8 |
0.1%~1% |
Anti osteoporosis |
|
|
Eucommiol |
C₁₅H₂₂O₄ |
22353-44-6 |
0.05%~0.5% |
neuroprotection |
|
|
Cyclohexene ether terpenes |
Aucubin |
C₁₅H₂₂O₉ |
479-98-1 |
0.05%~0.3% |
Antibacterial and antiviral |
|
Geniposide |
C17H24O10 |
24512-63-8 |
0.2%~1.5% |
Anti inflammatory and liver protective |
|
|
Geniposidic acid |
C16H22O10 |
27741-01-1 |
0.1%~0.8% |
hypoglycemia |
|
|
Flavonoids |
Quercetin |
C15H10O7 |
27741-01-1 |
0.05%~0.3% |
Antioxidant and anti-inflammatory properties |
|
Kaempferol |
C₁₅H₁₀O₆ |
520-18-3 |
0.02%~0.2% |
Antitumor and cardiovascular protection |
|
|
Polysaccharides |
Eucommia ulmoides polysaccharide |
(C6H10O5)n |
/ |
10%~30% |
immunoregulation |
|
Gutta-percha |
trans polyisoprene |
(C5H8)n |
9003-31-0 |
3%~10% |
material application |
High Purity
100% Natural
Compliant with standards
Stable supplying
Quality ensured
Versatile Applications
Application Fields Green max
1. Pharmaceuticals and Health Products
● Antihypertensive drugs: Compound preparations containing PDG (such as Du Zhong blood pressure reducing tablets)
● Bone Health: Calcium Compatibility (Prevention and Treatment of Osteoporosis)
● Liver protection products: Jiujiu Liver Protection Capsules
2. Functional Foods
● Eucommia ulmoides tea and beverages (popular in Japan as "Eucommia ulmoides health tea")
● Sports nutrition products (relieve muscle fatigue)
3. Cosmetics
● Anti aging essence (quercetin antioxidant)
● Hair products (improve hair follicle microcirculation)
4. Industrial use
● Eucommia ulmoides gum is used for medical materials such as elastic bandages and dental fillings.
Future R&D Directions
Structural Optimization
● PDG acetate derivatives: ↑Oral bioavailability from 8% to 35%
Synthetic Biology
● E. coli engineering: Lab-scale PDG production reaches 1.2g/L
New Clinical Applications
● Diabetic nephropathy: Phase II trials show 32% ↓proteinuria
Safety Profile
1. Toxicology
● Acute Toxicity: LD50 >10g/kg (practically non-toxic)
● Subchronic Toxicity: No organ pathology at 1g/kg/day×6 months (rats)
2. Drug Interactions
● Potentiation: Antihypertensives (requires BP monitoring)
● Contraindications: Anticoagulants (may prolong PT)
Usage Guidelines
1. Precision Dosing
|
Application |
Daily Dose |
Duration |
Optimal Combinations |
|
Bone Health |
250-300 mg |
≥6 months |
Vitamin K2 + calcium |
|
Blood Pressure |
200 mg bid |
Long-term |
Magnesium |
|
Exercise Recovery |
400 mg post-workout |
Acute use |
Curcumin |
2. Precautions:
● Dose reduction advised for hypotensive patients
● Take with meals to minimize GI irritation
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