Echinacea extract
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Basic information
Product Name: Echinacea extract
Appearance: Brown to yellow powder or granular
Standard Packing: 25kg/drum
Solubility: Dissolve in water and ethanol.
The Echinacea genus includes several species, primarily:
Echinacea purpurea – Most commonly used, whole plant extractable
Echinacea angustifolia – Higher active compound concentration in roots
Echinacea pallida – Less frequently used
Extraction Parts:
Aerial parts (flowers, leaves, stems) – Often used in water or alcohol extraction
Roots – Richer in active compounds but require longer growth cyclesQuality Standard: CP2020,JP,Customer Made
Core Active Components
1. Characteristic Compounds
Class |
Representative Compounds |
Content Range |
Bioactivity |
Caffeic Acid Derivatives |
Echinacoside |
0.5-4.0% |
Immunostimulation (↑macrophage phagocytosis) |
|
Chicoric acid |
0.3-2.5% |
Anti-HIV integrase (IC50=10 μM) |
Alkylamides |
Dodeca-2E,4E,8Z-trienoic acid isobutylamide |
0.1-0.8% |
CB2 receptor activation (analgesia) |
Polysaccharides |
Arabinogalactan (45kDa) |
2-8% |
T-cell proliferation (↑IL-2 secretion) |
Essential Oils |
Germacrene D |
0.05-0.3% |
Anti-RSV activity |
2.Tissue Distribution:
Roots: Highest alkylamide content (5-8× aerial parts)
Flowers: Richest in phenolic acids (3× leaves)
High Purity
100% Natural
Compliant with standards
Stable supplying
Quality ensured
Versatile Applications
Multitarget Pharmacological Activities
1. Immunomodulation
Innate immunity:
↑45% macrophage phagocytic activity
3× enhanced NK cell tumor cytotoxicity
2.Adaptive immunity:
Clinical Data: 1000mg/day ×10 days reduces cold duration by 1.8 days
2. Anti-Inflammatory & Analgesic
COX-2 inhibition (IC50=15 μM), 1/3 more potent than celecoxib
Peripheral CB2 activation (non-opioid analgesia)
3. Antiviral Spectrum
Virus |
Active Compound |
Inhibition Rate |
Mechanism |
Influenza (H1N1) |
Chicoric acid |
78% |
Hemagglutinin blockade |
Herpes simplex (HSV-1) |
Echinacin |
65% |
Viral DNA polymerase inhibition |
Coronavirus (229E) |
Alkylamides |
52% |
Viral envelope fusion interference |
Application Fields Green max
1. Pharmaceuticals:
● Immunostimulant: Polysaccharide-alkylamide capsules (for chemotherapy-induced leukopenia)
● Anticold Agent: Echinacoside sublingual spray (35% shorter illness duration)
2. Functional Foods:
● Respiratory Health: Echinacea + elderberry powder (flu season prophylaxis)
● Exercise Recovery: Alkylamides + curcumin (40% ↓muscle inflammation markers)
3. Cosmetics:
● Anti-Sensitive: 0.5% echinacoside + ceramides (skin barrier repair)
● Oral Care: Alkylamide mouthwash (inhibits Porphyromonas gingivalis)
Structural Optimization
Synthetic Biology
New Clinical Applications
Usage Guidelines
Precision Dosing
Application |
Daily Dose |
Duration |
Optimal Combinations |
Immune Support |
500-1000 mg |
8-12 weeks |
Vitamin D + zinc |
Cold Onset |
1000 mg tid |
10 days acute |
High-dose vitamin C |
Chronic Inflammation |
300 mg bid |
≥3 months |
Omega-3 fatty acids |
Precautions
Limit continuous use to 8 weeks (prevents immune tolerance)
Morning administration preferred (mild stimulant effect)
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