Berberine Hydrochloride
description1
description2
Basic Information
Product Name: Berberine Hydrochloride
Chemical Name: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride
Molecular Formula: C₂₀H₁₈ClNO₄
CAS No.:【 633-65-8】
Molecular weight: 372.822
Solubility: Easily soluble in boiling water, slightly soluble in cold water, and almost insoluble in cold ethanol, chloroform, and ether
Quality Standard: CP2020,JP,Customer Made
Specification
Test Items |
Standard |
Berberine Hydrochloride 【633-65-8】 |
≥97.0% by HPLC |
Loss on drying |
≤12.0% |
Residue on ignition |
≤0.2% |
Key Features
Multifunctional Benefits
Metabolic Regulation: Activates AMPK pathways to support blood sugar and lipid management, suitable for individuals with diabetes or obesity.
Antimicrobial & Anti-inflammatory: Inhibits pathogens like E. coli and Staphylococcus aureus, aiding in gastrointestinal infections.
Gut Health: Modulates intestinal microbiota, alleviating diarrhea and indigestion.
Natural Origin
Sourced from medicinal herbs, combining traditional efficacy with scientific validation.
High Purity
Advanced purification ensures ≥98% purity for optimal efficacy and stability.
road-spectrum antibacterial
Against a variety of Gram-positive, Gram-negative bacteria (e.g. Shigella, Escherichia coli, Staphylococcus aureus, Hemolytic streptococcus, pneumococcus, typhoid bacilli, etc
Pharmacological effects Green max
Berberine hydrochloride has a broad-spectrum antibacterial effect, and its mechanism of action mainly includes:
1. Interfere with bacterial metabolism: Inhibit the oxidation and decarboxylation process of pyruvate, an intermediate link in bacterial sugar metabolism.
2.Inhibit bacterial DNA replication Affect bacterial nucleic acid metabolism and interfere with the synthesis of their genetic material.
3. Damage to bacterial structure : It has a damaging effect on the cell membrane of bacteria and affects their barrier function.
4. Anti-inflammatory and immune regulation: It has a certain anti-inflammatory effect and can alleviate intestinal inflammatory responses; Some studies also show that it has a regulatory effect on intestinal immune function.
5. Astringent and antidiarrheal: It has an astringent effect on the intestinal mucosa and reduces the secretion of intestinal fluid.
Dosage & Administration
1.Adults: 100–300 mg, 2–3 times daily after meals (consult a physician for precise dosing).
2.Contraindications: Not for pregnant women or patients with hemolytic jaundice; avoid concurrent use with hypoglycemic drugs or antibiotics (medical supervision required).
Safety Profile
Clinical studies show minimal side effects (e.g., occasional bloating or constipation) at recommended doses, with no hepatorenal toxicity. Long-term use should include periodic health monitoring.
Please Send me email and you can get more what you want.
Such as product of Price, Specification, MOA, MSDS, Flow Chart, Packing details, Shipping Term, Payment Term, after Sale service and so on.
Our experts will solve them in no time.